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SMILES: [H][C@@]12CC[C@@]([H])([C@H](N1)C(=O)N1CC3(C1)CN(C3)c1c(cnc3sc(CC(F)(F)F)cc13)C(F)(F)F)C(=O)C2

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554121   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase 2A/Menin


(Homo sapiens (Human))		BDBM554121
PNG
(US11325921, Example 8)
Show SMILES [H][C@@]12CC[C@@]([H])([C@H](N1)C(=O)N1CC3(C1)CN(C3)c1c(cnc3sc(CC(F)(F)F)cc13)C(F)(F)F)C(=O)C2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 635n/an/an/an/an/an/a


TBA

Assay Description
Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2K64N9C
More data for this
Ligand-Target Pair