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SMILES: FC(F)c1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C2)C(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase 2A/Menin (Homo sapiens (Human))	BDBM554139 (US11325921, Example 26 | US11325921, Example 27) Show SMILES FC(F)c1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C2)C(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K64N9C
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A/Menin (Homo sapiens (Human))	BDBM554139 (US11325921, Example 26 | US11325921, Example 27) Show SMILES FC(F)c1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C2)C(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K64N9C
					More data for this Ligand-Target Pair