BDBM55814 5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylene]barbituric acid::5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylidene]-1,3-diazinane-2,4,6-trione::5-[[5-[2,5-bis(chloranyl)phenyl]-1H-pyrrol-2-yl]methylidene]-1,3-diazinane-2,4,6-trione::MLS000764848::SMR000290453::cid_5769678

SMILES: Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1

InChI Key: InChIKey=NLMUDDQWRFLCTF-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 55814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ubiquitin-conjugating enzyme E2I (Homo sapiens (Human))	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2V986G8
					More data for this Ligand-Target Pair
neutrophil cytosolic factor 1 (Homo sapiens (Human))	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M90723
					More data for this Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QN656Q
					More data for this Ligand-Target Pair
BZLF1 (Human herpesvirus 4)	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BC3X0T
					More data for this Ligand-Target Pair
SUMO1 activating enzyme subunit 1 (Homo sapiens (Human))	BDBM55814 (5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1 |(3.08,4.19,;4.61,4.35,;5.24,5.76,;6.77,5.92,;7.67,4.68,;9.21,4.84,;7.05,3.27,;5.52,3.11,;7.95,2.02,;9.49,2.02,;9.97,.56,;8.72,-.35,;8.72,-1.89,;10.06,-2.66,;10.06,-4.2,;8.72,-4.97,;11.39,-4.97,;12.72,-4.2,;14.06,-4.97,;12.72,-2.66,;11.39,-1.89,;11.39,-.35,;7.48,.56,)| Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BP0175
					More data for this Ligand-Target Pair