null

SMILES: CCn1nc(Cl)c2cnc(Nc3cn(nc3Cl)C3CCCN(CC3)S(C)(=O)=O)nc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 559623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM559623 (US11370796, Compound 51) Show SMILES CCn1nc(Cl)c2cnc(Nc3cn(nc3Cl)C3CCCN(CC3)S(C)(=O)=O)nc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description After the compound was dissolved in 100% DMSO at 10 mM, it was serially diluted to the range of 1 μM to 10 μM using biochemical LRRK2 assay...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z7J
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM559623 (US11370796, Compound 51) Show SMILES CCn1nc(Cl)c2cnc(Nc3cn(nc3Cl)C3CCCN(CC3)S(C)(=O)=O)nc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description After the compound was dissolved in 100% DMSO at 10 mM, it was serially diluted to the range of 1 μM to 10 μM using biochemical LRRK2 assay...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z7J
					More data for this Ligand-Target Pair