null

SMILES: COc1ccc2nc1OCCCOC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC2CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559731 (WO2022109117, Example 76) Show SMILES COc1ccc2nc1OCCCOC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC2CC1 |wD:16.17,19.20,25.26,(1.65,5.58,;3.17,5.74,;4.07,4.52,;3.42,3.13,;4.33,1.89,;5.9,1.98,;6.46,3.43,;5.6,4.72,;6.31,6.12,;7.46,7.16,;8.93,7.6,;10.47,7.46,;11.85,6.76,;12.89,5.59,;14.2,6.35,;13.41,4.06,;14.86,4.5,;15.37,5.94,;15.73,3.25,;14.81,2.04,;15.24,.58,;16.72,.22,;18.2,-.13,;17.07,1.71,;16.37,-1.26,;13.37,2.54,;12.76,1.09,;11.61,.01,;10.06,-.28,;9.79,1.24,;8.37,1.78,;7.11,.89,;7.4,-.66,;8.82,-1.24,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair