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null

SMILES: COc1cc(cc(OC)c1CN1CCC2(CN(C2)C(=O)CCOCCOc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1)-c1cn(C)c(=O)c2cnccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 565320
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein SSX2/Protein SSXT (Human)	BDBM565320 (US11414416, Compound D88 \| US11560381, Compound D8...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6H41
TBA					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [133-239] (Homo sapiens (Human))	BDBM565320 (US11414416, Compound D88 \| US11560381, Compound D8...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...				Citation and Details BindingDB Entry DOI: 10.7270/Q2571G8B
TBA					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [133-239] (Homo sapiens (Human))	BDBM565320 (US11414416, Compound D88 \| US11560381, Compound D8...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Procedure: His-Flag-BRD9 (P133-K239; Swiss Prot Q9H8M2; SEQ ID NO:1 mgsshhhhhhenlyfq/gdykddddkgslevlfqg/PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6H41
TBA					More data for this Ligand-Target Pair