null
SMILES: COc1cc(F)c(cc1F)-c1cc(Cn2cnc3c(N)ncnc23)c(cn1)N1CCC[C@@](N)(C1)[C@H](O)C(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase NSD2 (Homo sapiens (Human)) | BDBM567960 (US11420970, Example 161) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white... | Citation and Details BindingDB Entry DOI: 10.7270/Q27084N0 | |||||||||||
More data for this Ligand-Target Pair |