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SMILES: COc1ccc(-c2cc(Cn3cnc4c(N)ncnc34)c(cn2)N2CCC[C@@](N)(C2)[C@@H](O)C(F)F)c(c1)C(F)F

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 567962   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase NSD2


(Homo sapiens (Human))		BDBM567962
PNG
(US11420970, Example 163)
Show SMILES COc1ccc(-c2cc(Cn3cnc4c(N)ncnc34)c(cn2)N2CCC[C@@](N)(C2)[C@@H](O)C(F)F)c(c1)C(F)F |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a


TBA

Assay Description
This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...

Citation and Details

BindingDB Entry DOI: 10.7270/Q27084N0
More data for this
Ligand-Target Pair