BDBM56860 2-(2-chlorophenyl)-5-hydroxy-6-nitro-1-benzopyran-4-one::2-(2-chlorophenyl)-5-hydroxy-6-nitro-chromone::2-(2-chlorophenyl)-5-hydroxy-6-nitrochromen-4-one::2-(2-chlorophenyl)-6-nitro-5-oxidanyl-chromen-4-one::MLS000518333::SMR000462401::cid_5314968

SMILES: Oc1c(ccc2oc(cc(=O)c12)-c1ccccc1Cl)[N+]([O-])=O

InChI Key: InChIKey=TXSIWBDMPGEZMX-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 56860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM56860 (2-(2-chlorophenyl)-5-hydroxy-6-nitro-1-benzopyran-...) Show SMILES Oc1c(ccc2oc(cc(=O)c12)-c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H8ClNO5/c16-9-4-2-1-3-8(9)13-7-11(18)14-12(22-13)6-5-10(15(14)19)17(20)21/h1-7,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BV7F1T
					More data for this Ligand-Target Pair
NLRP3 protein (Homo sapiens (Human))	BDBM56860 (2-(2-chlorophenyl)-5-hydroxy-6-nitro-1-benzopyran-...) Show SMILES Oc1c(ccc2oc(cc(=O)c12)-c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H8ClNO5/c16-9-4-2-1-3-8(9)13-7-11(18)14-12(22-13)6-5-10(15(14)19)17(20)21/h1-7,19H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RN369N
					More data for this Ligand-Target Pair
NLRP3 protein (Homo sapiens (Human))	BDBM56860 (2-(2-chlorophenyl)-5-hydroxy-6-nitro-1-benzopyran-...) Show SMILES Oc1c(ccc2oc(cc(=O)c12)-c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H8ClNO5/c16-9-4-2-1-3-8(9)13-7-11(18)14-12(22-13)6-5-10(15(14)19)17(20)21/h1-7,19H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WD3Z10
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM56860 (2-(2-chlorophenyl)-5-hydroxy-6-nitro-1-benzopyran-...) Show SMILES Oc1c(ccc2oc(cc(=O)c12)-c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H8ClNO5/c16-9-4-2-1-3-8(9)13-7-11(18)14-12(22-13)6-5-10(15(14)19)17(20)21/h1-7,19H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TX3CTT
					More data for this Ligand-Target Pair