null

SMILES: OC1CCC(=CC1)c1ccc(cc1C(F)(F)F)C1=NNC(=O)OC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM568680 ((rac)-5-[4′-Hydroxy-2-(trifluoromethyl)-2...) Show SMILES OC1CCC(=CC1)c1ccc(cc1C(F)(F)F)C1=NNC(=O)OC1 |c:4,t:19| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280BTW
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM568680 ((rac)-5-[4′-Hydroxy-2-(trifluoromethyl)-2...) Show SMILES OC1CCC(=CC1)c1ccc(cc1C(F)(F)F)C1=NNC(=O)OC1 |c:4,t:19| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280BTW
					More data for this Ligand-Target Pair