BDBM5705 2-amino-5-thio-substituted thiazole 73::N-(5-{[2-(naphthalen-1-yl)ethyl]sulfanyl}-1,3-thiazol-2-yl)acetamide

SMILES: CC(=O)Nc1ncc(SCCc2cccc3ccccc23)s1

InChI Key: InChIKey=XCAVLMXPUGJLRY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/CycE (Homo sapiens (Human))	BDBM5705 (2-amino-5-thio-substituted thiazole 73 | N-(5-{[2-...) Show SMILES CC(=O)Nc1ncc(SCCc2cccc3ccccc23)s1 Show InChI InChI=1S/C17H16N2OS2/c1-12(20)19-17-18-11-16(22-17)21-10-9-14-7-4-6-13-5-2-3-8-15(13)14/h2-8,11H,9-10H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...				J Med Chem 45: 3905-27 (2002) Article DOI: 10.1021/jm0201520 BindingDB Entry DOI: 10.7270/Q2GT5KC3
					More data for this Ligand-Target Pair