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SMILES: Cc1cc(=O)cc(C)n1CC(=O)c1ccc(OC(F)F)c(OCC2CC2)c1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570708   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM570708
PNG
(US11440886, Example 49)
Show SMILES Cc1cc(=O)cc(C)n1CC(=O)c1ccc(OC(F)F)c(OCC2CC2)c1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/an/an/a


TBA

Assay Description
The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2TM7FBS
More data for this
Ligand-Target Pair