null

SMILES: CN[C@H]1CCCN(C1)c1ccnc2[nH]cc(-c3ccnnc3)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 572285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase MRCK alpha (Homo sapiens (Human))	BDBM572285 ((3S)-N-methyl-1-(3- pyridazin-4-yl-1H- pyrrolo[2,3...) Show SMILES CN[C@H]1CCCN(C1)c1ccnc2[nH]cc(-c3ccnnc3)c12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VD72PZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase MRCK beta (Homo sapiens (Human))	BDBM572285 ((3S)-N-methyl-1-(3- pyridazin-4-yl-1H- pyrrolo[2,3...) Show SMILES CN[C@H]1CCCN(C1)c1ccnc2[nH]cc(-c3ccnnc3)c12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.786	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VD72PZ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM572285 ((3S)-N-methyl-1-(3- pyridazin-4-yl-1H- pyrrolo[2,3...) Show SMILES CN[C@H]1CCCN(C1)c1ccnc2[nH]cc(-c3ccnnc3)c12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	44.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VD72PZ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM572285 ((3S)-N-methyl-1-(3- pyridazin-4-yl-1H- pyrrolo[2,3...) Show SMILES CN[C@H]1CCCN(C1)c1ccnc2[nH]cc(-c3ccnnc3)c12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VD72PZ
					More data for this Ligand-Target Pair