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SMILES: Cc1nccc2c(NC3(C)CC3)nc(nc12)-c1ccncc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574370   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase LATS1


(Homo sapiens (Human))		BDBM574370
PNG
(US11458138, Example 199)
Show SMILES Cc1nccc2c(NC3(C)CC3)nc(nc12)-c1ccncc1
PDB

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antibodypedia
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PC cid
PC sid
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US Patent
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
The LATS1 biochemical HTRF assay was performed using the HTRF KinEASE-STK S1 kit (CisBio, catalogue number 62ST1PEC) according to manufacturer's ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q21Z47NH
More data for this
Ligand-Target Pair