null

SMILES: CC(C)(C)Nc1cc(nc2cnccc12)-c1ccncc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 574381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase LATS2 (Homo sapiens (Human))	BDBM574381 (US11458138, Example 261) Show SMILES CC(C)(C)Nc1cc(nc2cnccc12)-c1ccncc1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q21Z47NH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase LATS1 (Homo sapiens (Human))	BDBM574381 (US11458138, Example 261) Show SMILES CC(C)(C)Nc1cc(nc2cnccc12)-c1ccncc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LATS1 biochemical HTRF assay was performed using the HTRF KinEASE-STK S1 kit (CisBio, catalogue number 62ST1PEC) according to manufacturer's ...				Citation and Details BindingDB Entry DOI: 10.7270/Q21Z47NH
					More data for this Ligand-Target Pair