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SMILES: NC1C2(CC2)CCC11CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM575653 ((6-((2-amino-3-chloropyridin-4-yl)thio)-3- (4-amin...) Show SMILES NC1C2(CC2)CCC11CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...				Citation and Details BindingDB Entry DOI: 10.7270/Q2028VS0
					More data for this Ligand-Target Pair