null

SMILES: CC(=O)N1CCN(CC1)c1ccc(CNC(=O)C2(CC2)c2ccc(OCc3ccc(nc3)C(F)(F)F)nn2)cc1F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM575706 (US11465982, Example 1.6) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CNC(=O)C2(CC2)c2ccc(OCc3ccc(nc3)C(F)(F)F)nn2)cc1F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KS6VSR
					More data for this Ligand-Target Pair