null
SMILES: CC(C)(O)C(C1CC1)N1Cc2ccc(F)c(c2C1=O)-c1ccccc1OCC(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ceramide glucosyltransferase (Homo sapiens (Human)) | BDBM576435 (WO2022115301, Example 21) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022115301 | n/a | n/a | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a |
TBA | Assay Description Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MK6H5S | |||||||||||
More data for this Ligand-Target Pair |