null

SMILES: CS(=O)(=O)N1CCC(C1)NCc1ccc(c(Cl)c1)-n1cc(cn1)-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM576876 ((+-)-4-(1-(2-Chloro-4- (((1- (methylsulfonyl) p...) Show SMILES CS(=O)(=O)N1CCC(C1)NCc1ccc(c(Cl)c1)-n1cc(cn1)-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DQ0
					More data for this Ligand-Target Pair