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SMILES: CO[C@@H]1CCN(CCCS(=O)(=O)N2CC[C@H](Nc3ncc(c(n3)-c3cnn(CC(C)(C)O)c3)C(F)(F)F)[C@H](F)C2)C1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576884   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1


(Homo sapiens (Human))		BDBM576884
PNG
(1-(4-(2-(((3R,4S)-3- Fluoro-1-((3-((R)-3- methox...)
Show SMILES CO[C@@H]1CCN(CCCS(=O)(=O)N2CC[C@H](Nc3ncc(c(n3)-c3cnn(CC(C)(C)O)c3)C(F)(F)F)[C@H](F)C2)C1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
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GoogleScholar
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PC cid
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UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a


TBA

Assay Description
CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2FX7DQ0
More data for this
Ligand-Target Pair