Found 4 hits for monomerid = 577168 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825]
(Homo sapiens (Human)) | BDBM577168
(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)Show SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2scnc12)C1CC1 | PDB MMDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672]
(Homo sapiens (Human)) | BDBM577168
(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)Show SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2scnc12)C1CC1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 90.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712]
() | BDBM577168
(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)Show SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2scnc12)C1CC1 | PDB MMDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736]
(Homo sapiens (Human)) | BDBM577168
(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)Show SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2scnc12)C1CC1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |