null

SMILES: COc1cccc(c1)[C@H](NCCN(C)C)C(=O)Nc1ccc(cc1)-c1cn[nH]c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM578434 ((S)—N-(4-(1H-pyrazol-4-yl)phenyl)-2-((2-(dimethyla...) Show SMILES COc1cccc(c1)[C@H](NCCN(C)C)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	258	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JGS
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 [1-552] (Homo sapiens (Human))	BDBM578434 ((S)—N-(4-(1H-pyrazol-4-yl)phenyl)-2-((2-(dimethyla...) Show SMILES COc1cccc(c1)[C@H](NCCN(C)C)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JGS
					More data for this Ligand-Target Pair