null

SMILES: CN(C)[C@H](CNC(=O)NCCN1C(=O)C=CC1=O)Cc1c(C)cc(O)cc1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 579543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM579543 (US11484525, Compound DD-144-ANTAGONIST-Covalent) Show SMILES CN(C)[C@H](CNC(=O)NCCN1C(=O)C=CC1=O)Cc1c(C)cc(O)cc1C |r,c:14| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JQ14V2
					More data for this Ligand-Target Pair
Mu-type opioid receptor [N127C] (Homo sapiens (Human))	BDBM579543 (US11484525, Compound DD-144-ANTAGONIST-Covalent) Show SMILES CN(C)[C@H](CNC(=O)NCCN1C(=O)C=CC1=O)Cc1c(C)cc(O)cc1C |r,c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JQ14V2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM579543 (US11484525, Compound DD-144-ANTAGONIST-Covalent) Show SMILES CN(C)[C@H](CNC(=O)NCCN1C(=O)C=CC1=O)Cc1c(C)cc(O)cc1C |r,c:14| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JQ14V2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM579543 (US11484525, Compound DD-144-ANTAGONIST-Covalent) Show SMILES CN(C)[C@H](CNC(=O)NCCN1C(=O)C=CC1=O)Cc1c(C)cc(O)cc1C |r,c:14| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JQ14V2
					More data for this Ligand-Target Pair