null
SMILES: Cc1ccc(s1)-c1cc2c(ccnc2[nH]1)-c1cc([nH]c(=O)c1)N1CCOCC1C(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human)) | BDBM580170 (4-[2-(5-Methyl-2-thienyl)-1H-pyrrolo[2,3-b]pyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ... | Citation and Details BindingDB Entry DOI: 10.7270/Q24J0JZJ | |||||||||||
More data for this Ligand-Target Pair |