null
SMILES: Cn1ncc2ccc(cc12)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2-Hydroxyacid oxidase 1 (Homo sapiens (Human)) | BDBM581222 (5-(4-(2-(1-methyl-1H-indazol- 6-yl)ethynyl)phenox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz... | Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG | |||||||||||
More data for this Ligand-Target Pair |