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SMILES: CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)[C@@H](C)C(F)(F)F)c1=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581554   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM581554
PNG
((R)-6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro...)
Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)[C@@H](C)C(F)(F)F)c1=O |r|
PDB
MMDB

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PC cid
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US Patent
n/an/a 0.260n/an/an/an/an/an/a


TBA

Assay Description
The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WS8Z24
More data for this
Ligand-Target Pair