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SMILES: NC1CC2CCC(C1)N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581904   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM581904
PNG
(US11510915, Example 259)
Show SMILES NC1CC2CCC(C1)N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 |TLB:9:8:4.5:1.2.7|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a


TBA

Assay Description
The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2NC6513
More data for this
Ligand-Target Pair