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SMILES: CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581938   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM581938
PNG
(US11510915, Example 293)
Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:22:23:26.25:28.30|
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0760n/an/an/an/an/an/a


TBA

Assay Description
The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2NC6513
More data for this
Ligand-Target Pair