BDBM58378 3-[2,5-bis(4-methoxyphenyl)-1-benzofuran-3-yl]prop-2-yn-1-ol::3-[2,5-bis(4-methoxyphenyl)-3-benzofuranyl]-2-propyn-1-ol::3-[2,5-bis(4-methoxyphenyl)benzofuran-3-yl]prop-2-yn-1-ol::MLS001144063::SMR000526358::cid_24747939

SMILES: COc1ccc(cc1)-c1oc2ccc(cc2c1C#CCO)-c1ccc(OC)cc1

InChI Key: InChIKey=ZBQBABMXASQMHH-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 58378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM58378 (3-[2,5-bis(4-methoxyphenyl)-1-benzofuran-3-yl]prop...) Show SMILES COc1ccc(cc1)-c1oc2ccc(cc2c1C#CCO)-c1ccc(OC)cc1 Show InChI InChI=1S/C25H20O4/c1-27-20-10-5-17(6-11-20)19-9-14-24-23(16-19)22(4-3-15-26)25(29-24)18-7-12-21(28-2)13-8-18/h5-14,16,26H,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
COUP transcription factor 2 isoform a (Homo sapiens (Human))	BDBM58378 (3-[2,5-bis(4-methoxyphenyl)-1-benzofuran-3-yl]prop...) Show SMILES COc1ccc(cc1)-c1oc2ccc(cc2c1C#CCO)-c1ccc(OC)cc1 Show InChI InChI=1S/C25H20O4/c1-27-20-10-5-17(6-11-20)19-9-14-24-23(16-19)22(4-3-15-26)25(29-24)18-7-12-21(28-2)13-8-18/h5-14,16,26H,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q21Z431S
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM58378 (3-[2,5-bis(4-methoxyphenyl)-1-benzofuran-3-yl]prop...) Show SMILES COc1ccc(cc1)-c1oc2ccc(cc2c1C#CCO)-c1ccc(OC)cc1 Show InChI InChI=1S/C25H20O4/c1-27-20-10-5-17(6-11-20)19-9-14-24-23(16-19)22(4-3-15-26)25(29-24)18-7-12-21(28-2)13-8-18/h5-14,16,26H,15H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair