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SMILES: CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4C(=O)O[C@@H](C)[C@H](C)c4n3)cc12

InChI Key:

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 587372   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 1


(Homo sapiens (Human))		BDBM587372
PNG
(US11534441, Compound 80)
Show SMILES CC[C@@](C)(N)c1cnc(OC2CC2)c2cnc(Nc3ccc4C(=O)O[C@@H](C)[C@H](C)c4n3)cc12 |r|
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
US Patent
n/an/a 0.0800n/an/an/an/an/an/a


TBA

Assay Description
Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...

Citation and Details

BindingDB Entry DOI: 10.7270/Q27S7SMZ
More data for this
Ligand-Target Pair