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SMILES: Clc1cccc(Nc2ncc(cn2)-c2cncc(N[C@H]3CCN(C3)C(=O)C=C)c2)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM588142 (1-[3-[[5-[2-(3- chloroanilino) pyrimidin-5-yl]-3-...) Show SMILES Clc1cccc(Nc2ncc(cn2)-c2cncc(N[C@H]3CCN(C3)C(=O)C=C)c2)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The BTK and EGFR biochemical assays utilize LANTHASCREEN® Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38XD6
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM588142 (1-[3-[[5-[2-(3- chloroanilino) pyrimidin-5-yl]-3-...) Show SMILES Clc1cccc(Nc2ncc(cn2)-c2cncc(N[C@H]3CCN(C3)C(=O)C=C)c2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	6.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The BTK and EGFR biochemical assays utilize LANTHASCREEN® Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38XD6
					More data for this Ligand-Target Pair