null
SMILES: FC(F)(F)Oc1ccccc1Nc1ncc(cn1)-c1cncc(NC2CN(C2)C(=O)C=C)n1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM588172 (1-[3-[[6-[2-[2- (trifluoromethoxy) anilino]pyrimid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 676 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The BTK and EGFR biochemical assays utilize LANTHASCREENŽ Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase... | Citation and Details BindingDB Entry DOI: 10.7270/Q2J38XD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM588172 (1-[3-[[6-[2-[2- (trifluoromethoxy) anilino]pyrimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The BTK and EGFR biochemical assays utilize LANTHASCREENŽ Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase... | Citation and Details BindingDB Entry DOI: 10.7270/Q2J38XD6 | |||||||||||
More data for this Ligand-Target Pair |