BindingDB PrimarySearch

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SMILES: CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589758
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.61	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-13 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-13 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-13 (Human)	BDBM589758 (US11559538, Example 189 \| US11559538, Example 21 \|...) Show SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair