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SMILES: CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589759   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.89n/an/an/an/an/an/a


TBA

Assay Description
Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interleukin-13


(Human)
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 257n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interleukin-4


(Human)
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.75n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interferon gamma receptor 1


(Homo sapiens (Human))
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.20n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.77n/an/an/an/an/an/a


TBA

Assay Description
Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interleukin-13


(Human)
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.49E+3n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interleukin-4


(Human)
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.58n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair
Interferon gamma receptor 1


(Homo sapiens (Human))
BDBM589759
PNG
(US11559538, Example 22 | US11559538, Example 54)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(C)cc(n1)C1COB(O)C1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.43n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2542SHJ
More data for this
Ligand-Target Pair