null

SMILES: CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 589767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8/9 (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM589767 (US11559537, Compound 5322) Show SMILES CC(C)(C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J7Z
					More data for this Ligand-Target Pair