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SMILES: CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 14


(Homo sapiens (Human))		BDBM590218
PNG
(US11560385, Compound 28A)
Show SMILES CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1 |c:4,THB:23:22:18.19:16|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a


TBA

Assay Description
Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.

Citation and Details

BindingDB Entry DOI: 10.7270/Q2445RDM
More data for this
Ligand-Target Pair