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SMILES: FC(F)(F)c1cc(Cl)cc(c1)N1CC[C@@H](C1)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592926   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30 [57-517]


(Homo sapiens (Human))		BDBM592926
PNG
((3S)-1-(3-chloro-5-(trifluoromethyl)phenyl)- N-((1...)
Show SMILES FC(F)(F)c1cc(Cl)cc(c1)N1CC[C@@H](C1)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N |r,THB:26:25:19.20:22.23|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/an/an/a


TBA

Assay Description
USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2NZ8CKC
More data for this
Ligand-Target Pair