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Enter Data

null

SMILES: Cc1ccc(cc1)-n1cc(Cn2c3ccsc3c(C(O)=O)c(O)c2=O)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 594827
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair
Exonuclease 1 (Human)	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair
Exonuclease 1 (Human)	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM594827 (US11584755, Example 116 \| US11584755, Example 117) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PR80W3
TBA					More data for this Ligand-Target Pair