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SMILES: COc1cc2ccccc2cc1C[C@@H]1CN[C@H](C1)C(=O)N[C@@H](C)C(=O)NCc1ccc(N)nc1C
InChI Key:
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mannan-binding lectin serine protease 2 (Homo sapiens) | BDBM595390 (US11584714, Compound 1478) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | <500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mannan-binding lectin serine protease 2 (Mouse) | BDBM595390 (US11584714, Compound 1478) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| thrombin (Homo sapiens (Human)) | BDBM595390 (US11584714, Compound 1478) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
