BDBM60564 US9102669, 76
SMILES: Fc1ccc2ccn(C3CCN(CC3)c3ccc(nn3)-c3ccc(nc3)C(F)(F)F)c2c1
InChI Key: InChIKey=XJBJQQCHYUCQGQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stearoyl-CoA desaturase 1 (SCD1) (Rattus norvegicus (Rat)) | BDBM60564 (US9102669, 76) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV US Patent | Assay Description The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e... | US Patent US9102669 (2015) BindingDB Entry DOI: 10.7270/Q2BC3X9V | |||||||||||
More data for this Ligand-Target Pair |