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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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Ki
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null
SMILES:
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F
InChI Key:
Find this compound or compounds like it in BindingDB or PDB:
Substructure
Similarity at least:
must be >=0.5
Exact match
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found
4
hits for monomerid = 614968
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614968
(US20230271939, Example 6)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
0.800
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614968
(US20230271939, Example 6)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
2.10
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614968
(US20230271939, Example 6)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
49.3
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614968
(US20230271939, Example 6)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
6.70
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
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