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SMILES: Nc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614978   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
eIF-2-alpha kinase GCN2


(Homo sapiens (Human))
BDBM614978
PNG
(US20230271939, Example 16)
Show SMILES Nc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.70n/an/an/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


BindingDB Entry DOI: 10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2


(Homo sapiens (Human))
BDBM614978
PNG
(US20230271939, Example 16)
Show SMILES Nc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


BindingDB Entry DOI: 10.7270/Q2Q244CX
More data for this
Ligand-Target Pair