null

SMILES: COc1n[nH]c2ncc(cc12)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cnc2OC)c1F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
eIF-2-alpha kinase GCN2 (Homo sapiens (Human))	BDBM614999 (US20230271939, Example 37) Show SMILES COc1n[nH]c2ncc(cc12)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cnc2OC)c1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent									US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2Q244CX
					More data for this Ligand-Target Pair
eIF-2-alpha kinase GCN2 (Homo sapiens (Human))	BDBM614999 (US20230271939, Example 37) Show SMILES COc1n[nH]c2ncc(cc12)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cnc2OC)c1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent									US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2Q244CX
					More data for this Ligand-Target Pair