null

SMILES: CN(C1CC[C@@H](CC1)N(CC1COCCO1)c1ccc2OCOc2c1)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol kinase alpha (Homo sapiens)	BDBM615878 (US20230271954, Compound 177 | cis-8-((4-(((1,4-dio...) Show SMILES CN(C1CC[C@@H](CC1)N(CC1COCCO1)c1ccc2OCOc2c1)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N |r,wU:5.8,(-2.67,-3.53,;-2.67,-1.99,;-1.33,-1.22,;,-1.99,;1.33,-1.22,;1.33,.32,;,1.09,;-1.33,.32,;2.67,1.09,;4,.32,;5.33,1.09,;5.33,2.63,;6.67,3.4,;8,2.63,;8,1.09,;6.67,.32,;2.67,2.63,;1.33,3.4,;1.33,4.94,;2.67,5.71,;2.99,7.22,;4.52,7.38,;5.15,5.97,;4,4.94,;4,3.4,;-4,-1.22,;-4,.32,;-2.67,1.09,;-1.33,1.86,;-5.33,1.09,;-5.33,2.63,;-6.67,.32,;-8,1.09,;-6.67,-1.22,;-8,-1.99,;-8,-3.53,;-6.67,-4.35,;-5.33,-3.53,;-5.33,-1.99,;-6.67,-5.89,;-6.67,-7.43,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari									J Med Chem 50: 4214-21 (2007) BindingDB Entry DOI: 10.7270/Q22B935K
					More data for this Ligand-Target Pair
Diacylglycerol kinase zeta (Homo sapiens)	BDBM615878 (US20230271954, Compound 177 | cis-8-((4-(((1,4-dio...) Show SMILES CN(C1CC[C@@H](CC1)N(CC1COCCO1)c1ccc2OCOc2c1)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N |r,wU:5.8,(-2.67,-3.53,;-2.67,-1.99,;-1.33,-1.22,;,-1.99,;1.33,-1.22,;1.33,.32,;,1.09,;-1.33,.32,;2.67,1.09,;4,.32,;5.33,1.09,;5.33,2.63,;6.67,3.4,;8,2.63,;8,1.09,;6.67,.32,;2.67,2.63,;1.33,3.4,;1.33,4.94,;2.67,5.71,;2.99,7.22,;4.52,7.38,;5.15,5.97,;4,4.94,;4,3.4,;-4,-1.22,;-4,.32,;-2.67,1.09,;-1.33,1.86,;-5.33,1.09,;-5.33,2.63,;-6.67,.32,;-8,1.09,;-6.67,-1.22,;-8,-1.99,;-8,-3.53,;-6.67,-4.35,;-5.33,-3.53,;-5.33,-1.99,;-6.67,-5.89,;-6.67,-7.43,)| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari									J Med Chem 50: 4214-21 (2007) BindingDB Entry DOI: 10.7270/Q22B935K
					More data for this Ligand-Target Pair