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SMILES: CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 621169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.0350	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 [D835V] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.0140	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (D835Y) (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [572-603] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 [K663Q] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [N841I] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.0990	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [R834Q] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V] (Homo sapiens (Human))	BDBM621169 (6-(6- (difluoromethyl)imidazo[1,2- a]pyridin-3-yl)...) Show SMILES CC1(C)NCCC1Nc1cccc(n1)-c1cnc2ccc(cn12)C(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	0.00900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair