null

SMILES: CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc34)cc2)cc1

InChI Key: InChIKey=SBFAEXIVVNAVTH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 62243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM62243 (4-(2,3-dihydroindol-1-ylmethyl)-N-(4-ethoxyphenyl)...) Show SMILES CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc34)cc2)cc1 Show InChI InChI=1S/C24H24N2O2/c1-2-28-22-13-11-21(12-14-22)25-24(27)20-9-7-18(8-10-20)17-26-16-15-19-5-3-4-6-23(19)26/h3-14H,2,15-17H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2Z899VD
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM62243 (4-(2,3-dihydroindol-1-ylmethyl)-N-(4-ethoxyphenyl)...) Show SMILES CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc34)cc2)cc1 Show InChI InChI=1S/C24H24N2O2/c1-2-28-22-13-11-21(12-14-22)25-24(27)20-9-7-18(8-10-20)17-26-16-15-19-5-3-4-6-23(19)26/h3-14H,2,15-17H2,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...				ACS Med Chem Lett 2: 780-785 (2011) Article DOI: 10.1021/ml200158b BindingDB Entry DOI: 10.7270/Q2H9966Z
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM62243 (4-(2,3-dihydroindol-1-ylmethyl)-N-(4-ethoxyphenyl)...) Show SMILES CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc34)cc2)cc1 Show InChI InChI=1S/C24H24N2O2/c1-2-28-22-13-11-21(12-14-22)25-24(27)20-9-7-18(8-10-20)17-26-16-15-19-5-3-4-6-23(19)26/h3-14H,2,15-17H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...				ACS Med Chem Lett 2: 780-785 (2011) Article DOI: 10.1021/ml200158b BindingDB Entry DOI: 10.7270/Q2H9966Z
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM62243 (4-(2,3-dihydroindol-1-ylmethyl)-N-(4-ethoxyphenyl)...) Show SMILES CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc34)cc2)cc1 Show InChI InChI=1S/C24H24N2O2/c1-2-28-22-13-11-21(12-14-22)25-24(27)20-9-7-18(8-10-20)17-26-16-15-19-5-3-4-6-23(19)26/h3-14H,2,15-17H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PR7TDC
					More data for this Ligand-Target Pair