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SMILES: CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3c(ccnc23)N(C)C)n1-c1ccccc1F

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 624862   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-2


(Homo sapiens (Human))		BDBM624862
PNG
(US20230322721, Example 22)
Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3c(ccnc23)N(C)C)n1-c1ccccc1F |r,wU:15.18,wD:13.13,(-10.68,-4.06,;-9.47,-3.11,;-9.63,-1.58,;-8.38,-.68,;-6.97,-1.3,;-5.73,-.4,;-5.89,1.13,;-7.3,1.76,;-8.54,.86,;-4.64,2.04,;-4.64,3.58,;-3.18,4.06,;-2.27,2.81,;-.73,2.81,;.36,1.72,;1.44,2.81,;.36,3.9,;2.98,2.81,;3.75,1.48,;2.98,.14,;5.29,1.48,;6.06,2.81,;7.6,2.81,;8.37,1.48,;7.6,.14,;8.37,-1.19,;7.6,-2.53,;6.06,-2.53,;5.29,-1.19,;6.06,.14,;9.91,-1.19,;10.68,.14,;10.68,-2.53,;-3.18,1.56,;-2.7,.1,;-3.73,-1.05,;-3.26,-2.51,;-1.75,-2.83,;-.72,-1.69,;-1.2,-.22,;-.17,.92,)|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair