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SMILES: COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 625604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [1-18,20-1210,T790M] (Homo sapiens (Human))	BDBM625604 (US20230322822, Compound 4) Show SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1 Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	43.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor [1-18,20-1210,C797S] (Homo sapiens (Human))	BDBM625604 (US20230322822, Compound 4) Show SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	80.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM625604 (US20230322822, Compound 4) Show SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	815	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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egfr-c797s/ t790m/del19 (Homo sapiens (Human))	BDBM625604 (US20230322822, Compound 4) Show SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor [L858R,T790M,C797S] (Homo sapiens (Human))	BDBM625604 (US20230322822, Compound 4) Show SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(C)c(Nc2ccc(C)cc2P(C)(C)=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair