BindingDB logo
myBDB logout

null

SMILES: COCn1c2nc(Nc3ccccc3)ncc2ccc1=O

InChI Key: InChIKey=QBBAIJFXDFLCKG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6260   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C]


(Homo sapiens (Human))		BDBM6260
PNG
(8-(methoxymethyl)-2-(phenylamino)-7H,8H-pyrido[2,3...)
Show SMILES COCn1c2nc(Nc3ccccc3)ncc2ccc1=O
Show InChI InChI=1S/C15H14N4O2/c1-21-10-19-13(20)8-7-11-9-16-15(18-14(11)19)17-12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.15E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...

J Med Chem 43: 4606-16 (2000)


Article DOI: 10.1021/jm000271k
BindingDB Entry DOI: 10.7270/Q25B00N4
More data for this
Ligand-Target Pair