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SMILES: CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2OC(C)(Oc2c1C)[C@@H]1CC[C@@H](CC1)NC1COC1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636217   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EZH2


(Homo sapiens (Human))		BDBM636217
PNG
(US20230365541, Compound 61, isomer 2)
Show SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2OC(C)(Oc2c1C)[C@@H]1CC[C@@H](CC1)NC1COC1 |r,wU:26.28,29.35,(-8.52,-6.52,;-8.52,-4.98,;-9.85,-4.21,;-11.19,-4.98,;-12.52,-4.21,;-13.85,-4.98,;-12.52,-2.67,;-11.19,-1.9,;-11.19,-.36,;-9.85,-2.67,;-8.52,-1.9,;-7.19,-2.67,;-5.85,-1.9,;-5.85,-.36,;-4.52,-2.67,;-4.52,-4.21,;-3.19,-4.98,;-3.19,-6.52,;-1.85,-4.21,;-.39,-4.68,;.52,-3.44,;1.85,-4.21,;-.39,-2.19,;-1.85,-2.67,;-3.19,-1.9,;-3.19,-.36,;1.85,-2.67,;3.19,-3.44,;4.52,-2.67,;4.52,-1.13,;3.19,-.36,;1.85,-1.13,;5.85,-.36,;7.19,-1.13,;7.59,-2.62,;9.07,-2.22,;8.67,-.73,)|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.25n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair